The Senior Scientist I, Chemistry, will work in the drug discovery team to enhance the company pipeline of drugs to treat human diseases. The successful candidate will be an experienced PhD chemist/medicinal chemist with 1+ years of experience in the pharmaceutical or biotech industry. This position will report to the Principal Investigator (Chemistry) and is located in our state-of-the-art research facility near the University of Kansas in Lawrence, Kansas.
What You’ll Do:
• Contribute scientifically and intellectually to Deciphera kinase inhibitor discovery programs especially in the area of medicinal chemistry
• Design and implement synthetic routes to prepare proprietary small molecules for biological testing in assigned projects
• Track structure activity relationships and optimizing potency, selectivity, and pharmaceutical properties of small molecules for research programs
• Manage interdisciplinary engagement with others in the organization and with various CROs in the areas of kinase inhibitor switch control technology, structure-based drug design, kinase biochemistry, kinase cellular biology, and pharmacology/pharmaceutics
• Generate reports and presentations as required by the organization, and providing input on intellectual property activities
• Adhere to corporate policies including safety, FDA compliance and regulatory matters
• Values other people and promotes the welfare of the organization and colleagues
• Ph.D. in organic or medicinal chemistry with 1+ years of industrial or post-doctoral experience in synthetic organic chemistry / drug discovery or equivalent experience
• High level of creativity and productivity with strong synthetic chemistry problem solving skills
• Demonstrated excellence in organic synthesis, conversant with the current literature
• In-depth knowledge and hands-on experience with a wide range of techniques in synthesis, purification, and spectroscopic characterization of novel compounds (NMR, LC-MS, HPLC, etc.)
• Experience using the concepts and tools of structure-based drug design
• Excellent oral and written communication skills
• Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team and maintain effective working relationships
• Effective oral and scientific/technical writing communication skills
• Demonstrated proficiency using MS Office applications is required
Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $107,000 - $148,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.
Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
Benefits:
Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!
EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.
...shows up and brings positive energy Open to feedback and love a good challenge What We Offer: &##127757; 100% Remote Work from home or wherever youre most productive &##128198; Flexible Schedule Set your own hours around your life &##128218; Full...
Fall 2025 Training & Compliance Intern (IINE Boston)The International Institute of New England is a 501(c)(3) non-profit serving refugees and immigrants in Boston, MA, Lowell, MA, and Manchester, NH. The Institute offers internships to students, graduate students, and...
...you to be a part of our growing team. Recognized by Food & Wine, Bon Appetit, the James Beard Foundation, and awarded 1 star by Michelin, The Dabney, is looking to bring energetic, enthusiastic and passionate hospitality professionals to its restaurant that serves seasonal...
...Requisition No:855297 Agency: Department of Health Working Title: COMMUNITY HEALTH NURSE - 64054974Pay Plan: Career Service Position Number:64054974 Salary: $56,000 - $57.844.80 Posting Closing Date: 08/27/2025 Total Compensation Estimator Job...
...About the Job: The Dog Wizard is a dog training franchise that has been in business for 18 years. It's Not Magic. It's Dog Training Done Right! We pride ourselves on customer service, delivering excellent standards of care in training, and the integrity of the people...